What are Endocrine Disrupting Chemicals?
Hormonal system as a network of chemical messengers (hormones) that circulate and transmit "information" necessary to examine specific sites on the function and development regulated by the body. This ongoing collaborative interactions play a key role in keeping the body in balance.
In the development of a male fetus, for example, hormones released by the brain to stimulate the production of the male hormone testosterone, transmits information on the reproductive system, to initiate the development of male sexual organs, and other characteristics of men. If too much testosterone is produced, intends to stimulate the brain to reduce its production levels and testosterone.
Very small amounts of endocrine disruptors can interfere or "disrupt" natural action of hormones go "message" wrong in certain organs and lead to changes in morphology, physiology, growth, reproduction, development and behavior. These changes had disorders related to the endocrine system such as reproductive failure, deformation of reproductive organs and cancer, reduced fertility, altered sex differentiation, metabolic disorders (such as obesity and diabetes mammals), immune dysfunction and cognitive impairment, among other associated effects.
Why EDC different from other toxic chemicals?
What makes this particular chemicals that mimic / interfere with the role of hormones naturally present in very low concentrations. Thus, a very small amount of EDC enough to cause the effect. If abnormal hormonal signals are sent in the early stages of life, made a mistake and "programming error" is set, which will inevitably lead to disease and dysfunction in later life, caused any cascade of events . This means that the unborn (open their mothers), infants and children are particularly vulnerable to the SED.
When exposed to young people and adults are small amounts of endocrine disrupting effects vary biological system of the adult can compensate for small changes, without causing illness. In classical risk assessment of toxic chemicals tests were performed mainly in adults and therefore are not able to detect the effects of low doses of EES minors. In addition, these tests are required level of security under which the effect can be considered safe. But scientists warn that the REE no safe level of exposure during early life stages of development and growth. These observations, together with the fact that at present there are very few tests in the assessment of toxic chemicals that endocrine disruption in particular note that some EDCs still visible wrongly classified as safe.
State-of-the-science of endocrine disruptors
There is much uncertainty regarding the diseases that are caused by these chemicals and what raw biochemical reactions in the long cascade of events that lead to the disease. In laboratory studies, scientists show that green 2EDCs overdose presented early in life to endocrine disorders, and although some proposals were also given in many cases, the exact mechanism of investigation course. For example, one of the violations in the endocrine system of the developing animal "imposex" in sea snails, in the state "of masculizination" when female snails to grow a penis, which blocks their reproduction, after the agent biocide tributyltin paint (TBT) TBT paints should be widely used in the 80s on ships hulls to prevent attachment of marine organisms to reduce boat speed and cause corrosion of the metal. The small drops of solid waste in the twenty-pool 50x25 meters is sufficient for "imposex" lead (!!), but why this occurs, more than 40 years of continuous investigation. OTC finally completely banned in 2008 due to persistent signs of harmful effects to aquatic organisms.
In such cases, if the risk to humans, animals and the environment to health have been found, but the scientific evidence is insufficient for a full risk assessment and the use of security measures, the EU should apply the precautionary principle and regulate the production and distribution to avoid in this case EDC more potential damage.
EDC, enter Europe's position and create a "political crimes".
Because of its unusual effects, EDC, were on the agenda of the European Union since 1999, when the "Community Strategy for endocrine" (COM (1999) 706), adopted in anticipation of research endocrine disruptors, to understand their actions determine his summer and gradually remove them from the market in Europe, step by step EDC included in the legislation on chemicals (Registration, Evaluation, Authorisation and Restriction of Chemicals REACH DCE VRD ;. , medical equipment, cosmetics), but it was a plant protection product EC Regulation 1107/2009 (PPP R), which entered into force in 2011 to regulate pesticides, the first law, the precautionary principle applies on endocrine disruptors and falling under the criteria "based on the risk of failure" applied the carcinogenic and toxic to reproduction of connections all DMS properties of pesticides is considered dangerous and should be banned (hence the term "cut- off "). Since pesticide residues are found in our food and decided against the use of these pesticides is certainly a wise decision. Criteria chiaroscuro EDS were also in biocidal products in the EU 528/2012 Regulation (BPR), which entered into force in 2013 included.
Identify Ironically, pesticides and biocides legislation before determining endocrine disruptors criteria. This has made the objective criteria for industry and environment industry facilities in the EU, the benefits of the use of pesticides in agriculture and intensive agriculture, with all kinds of tactics on side effects that cause these chemicals and the fact that to create the EDC as a whole.
PAN Europe is closely following the selection criteria process to identify endocrine disruptors to the Commission on the basis of the state of science on endocrine disruptors that protect measuring human health, future generations and the environment against the Order Select exposure adequate criteria to these chemicals.
No comments :
Post a Comment