With vaginal microbes associated with premature birth?
Monday, August 17, 2015 (HealthDay News) Researchers have learned how millions of microbes carried in the body of your health. Now connect a new study, premature birth to a specific kind of bacteria in the mixture vagina.
"Our discovery is important because it allows us to help women identify an increased risk of preterm labor by measuring the types of bacteria in the vagina in the early stages of pregnancy when there is still time to intervene and try to to reduce the risk, "said study co-author Dr. David Relman, professor of medicine at Stanford University in California.
But it will not happen any time soon. It is too early, so germs and premature births are associated in fact know. And if they do, the researchers are not sure they are connected.
"Premature birth is an extremely important issue in the United States and other countries around the world because of the increased likelihood of death or disability," said Relman.
Approximately 450,000 babies born prematurely over three weeks at the beginning of each year in the United States, researchers say in addition to information.
It is now known that the human body is filled with beneficial microbes. These larger microbes that cells, at least 10 times and offer a number of benefits, including protection against germs that can make people sick, said study lead author Dr. Daniel DiGiulio, researcher and clinical professor of medicine at Stanford.
In the new study, the researchers examined the microbes of the gut, mouth and vagina of 49 women. The samples were to take a week during pregnancy and in the months to one year after birth. Fifteen of the women who delivered prematurely.
Those who gave premature birth, had probably found greater bacterial diversity in the vagina, the study. Women are particularly prone to premature birth, if you give this model bacteria for several weeks.
In some cases, the germ diverse community it relatively early in pregnancy, DiGiulio said. "This is important because more than half of pregnant women who develop spontaneous premature delivery, we will never be able to predict that their baby will be born prematurely or determine after the event, why it happened," he said .
One theory is that the bacteria of the immune system, associated proteins produced and swelling induced labor wherein DiGiulio. "Many of these proteins, such as a group of related molecules called" cytokines "is also thought to play a role in the introduction of healthy work," he said.
Dr. Josef Neu, professor of neonatology at the University of Florida College of Medicine in Gainesville, noted that the study results are limited. While they are interesting, he said, the data do not prove that some bacterial structures associated with prematurity.
"Preliminary data indicate the number of adequately studied, and the absence of a clear how changes in vaginal bacteria can cause premature birth is the considerable additional search mechanism is needed," said Noah.
Examination of vaginal bacteria could one day become routine, but not enough evidence to support now, he said.
Finally, it can be treated with antibiotics in order to adjust the composition of bacteria in the vagina, where it. "It is possible and even likely that some form of microbial treatment in the future, which are designed to reduce the risk of preterm birth," said Noah.
Dr. Molly Stout, Associate Professor of Maternal Fetal Medicine at Washington University in St. Louis, agreed that the results have the potential to change practice. "All this knowledge and understanding, hopefully, we will be on how to better screening and treatment of preterm birth," she said.
The study is published in the Aug. 17 issue of the Proceedings of the National Academy of Sciences.
Monday, August 17, 2015 (HealthDay News) Researchers have learned how millions of microbes carried in the body of your health. Now connect a new study, premature birth to a specific kind of bacteria in the mixture vagina.
But it will not happen any time soon. It is too early, so germs and premature births are associated in fact know. And if they do, the researchers are not sure they are connected.
"Premature birth is an extremely important issue in the United States and other countries around the world because of the increased likelihood of death or disability," said Relman.
Approximately 450,000 babies born prematurely over three weeks at the beginning of each year in the United States, researchers say in addition to information.
It is now known that the human body is filled with beneficial microbes. These larger microbes that cells, at least 10 times and offer a number of benefits, including protection against germs that can make people sick, said study lead author Dr. Daniel DiGiulio, researcher and clinical professor of medicine at Stanford.
In the new study, the researchers examined the microbes of the gut, mouth and vagina of 49 women. The samples were to take a week during pregnancy and in the months to one year after birth. Fifteen of the women who delivered prematurely.
Those who gave premature birth, had probably found greater bacterial diversity in the vagina, the study. Women are particularly prone to premature birth, if you give this model bacteria for several weeks.
In some cases, the germ diverse community it relatively early in pregnancy, DiGiulio said. "This is important because more than half of pregnant women who develop spontaneous premature delivery, we will never be able to predict that their baby will be born prematurely or determine after the event, why it happened," he said .
One theory is that the bacteria of the immune system, associated proteins produced and swelling induced labor wherein DiGiulio. "Many of these proteins, such as a group of related molecules called" cytokines "is also thought to play a role in the introduction of healthy work," he said.
Dr. Josef Neu, professor of neonatology at the University of Florida College of Medicine in Gainesville, noted that the study results are limited. While they are interesting, he said, the data do not prove that some bacterial structures associated with prematurity.
"Preliminary data indicate the number of adequately studied, and the absence of a clear how changes in vaginal bacteria can cause premature birth is the considerable additional search mechanism is needed," said Noah.
Examination of vaginal bacteria could one day become routine, but not enough evidence to support now, he said.
Finally, it can be treated with antibiotics in order to adjust the composition of bacteria in the vagina, where it. "It is possible and even likely that some form of microbial treatment in the future, which are designed to reduce the risk of preterm birth," said Noah.
Dr. Molly Stout, Associate Professor of Maternal Fetal Medicine at Washington University in St. Louis, agreed that the results have the potential to change practice. "All this knowledge and understanding, hopefully, we will be on how to better screening and treatment of preterm birth," she said.
The study is published in the Aug. 17 issue of the Proceedings of the National Academy of Sciences.
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